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Thus, it was reported that median IGF-I and IGFBP-5 mRNA levels in resting young muscle are more than twice higher than those in elderly muscle[354], and aging is associated with decreases in IGF-IR content and IGF-IR phosphorylation in muscle[355]

36 P-Glycoprotein The olfactory epithelium has a slower mucociliary clearance time than the respiratory epithelium because of the absence of motile cilia